A study published in the Lancet Monday suggests polluted air leads to premature deaths from antimicrobial resistance (AMR)—highlighting the need for biotech solutions for AMR and emissions.
What we already knew: One of the deadliest air pollutants, PM2.5, carries antibiotic-resistant bacteria and antibiotic-resistance genes, which can cause infections when people inhale them, found a 2019 study.
What’s new: AMR from PM2.5 was associated with 480,000 premature deaths in 2018, finds the new study.
But there’s hope: If World Health Organization (WHO) standards for reducing PM2.5 are reached by 2050, AMR-associated deaths would fall by 16.8%, the study says.
The One Health challenge: Cleaner air is key to the One Health approach, which recognizes the relationship between the health of humans, animals, and the environment. Biotech solutions like biofuels can reduce particulate pollution.
The drug development challenge: The market is broken, says everyone from BIO to the London School of Economics and Nature. Antibiotic stewardship requires these drugs to be used sparingly, making development “risky and relatively unprofitable.”
A policy solution: The PASTEUR Act, proposed legislation in which the government would “pay for consistent access to novel antimicrobials with payments that are decoupled from the volume of antimicrobials used,” explains BIO’s Director of Infectious Disease Policy,Emily Wheeler.
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